For the sterilization of water, solvents, and aqueous liquids.
PNM filters are validated cartridge and capsule filters made using long-proven, absolute rated, Nylon 6,6 membrane. These filters are used for the sterilization of water, solvents, and aqueous liquids. Pore sizes range from 0.10 to 0.65 µm, and the filter sizes scale from laboratory to full production using identical materials to ensure consistent results.
The PNM filter’s broad chemical compatibility makes it a good fit for the filtration of solvents and other harsh chemicals. These filters are optimized for flow, high retention, and chemical compatibility. They are flushed to remove manufacturing debris and reduce extractables. Products are 100% integrity tested. PNM capsules are available pre-sterilized.
Applications
- SVPs & LVPs
- Diagnostics
- Buffers
- WFI, Water Purification
- Non-protein solutions
- Chemicals
Features and Benefits
PNM is a family of pharmaceutical-grade Nylon 6,6 membrane sterilizing filters.
- Optimized for flow, high retention, and chemical compatibility
- Flushed to remove manufacturing debris and reduce extractables
- Pore sizes range from 0.10 to 0.65 µm
Filtration Area
View Data Sheet for further product information:
- Integrity test specifications
- Materials of construction
- Operating parameters
- Sanitization and sterilization
- Regulation & compliance
PNM filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms listed below (0.10μm and 0.22μm meet the FDA definition of sterilizing grade filters).
- 0.10μm: Brevundimonas diminuta
- 0.22μm: Brevundimonas diminuta
- 0.45μm: Serratia marcescens
- 0.65μm: Saccharomyces cerevisiae
Quality Assurance
PNM filters are 100% integrity tested. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes.
PNM Cartridges
Available from 5-40 inches in length with several end connections and O-ring options.
PNM Capsules
These filters are PNM cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. PNM Capsules are available pre-sterilized.
