PTM Filters

PTM filters are constructed using a Polytetrafluoroethylene (PTFE) membrane and are validated for sterilizing filtration of gases and non-aqueous liquids. Pore sizes range from 0.10 to 5.0 µm and the filter sizes scale from laboratory to full production using identical materials to ensure consistent results.

The hydrophobic PTM filters resist wetting by airborne water droplets, making them ideal for air and gas applications. The broad chemical compatibility of the PTM filters makes them well-suited for aggressive solvents and other non-aqueous liquids. Each cartridge module is individually tested using the water intrusion method before it is released from manufacture.

Applications

• Compressed Air
• Pressurized Gases
• Fermentation Air
• Solvents
• Tank Vents

Features and Benefits

PTM Filters are a family of validated Polytetrafluoroethylene (PTFE) membrane products for the sterilization of process gas applications and tank vents.

• Hydrophobic - filters resist wetting by airborne water droplets, making them ideal for air and gas applications
• Broad chemical compatibility
• Well suited for aggressive solvents and other non-aqueous liquids
• Pore sizes range from 0.10 to 5.0 micron 

Filtration Area

For the following product information, click on the datasheet below:

• Integrity test specifications
• Flow rates for all pore sizes
• Materials of construction
• Operating parameters
• Sanitization and sterilization
• Regulatory & compliance

Validation

PTM filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms (0.10µm and 0.22µm meet the FDA definition of sterilizing grade filters).

• 0.10µm: Brevundimonas diminuta
• 0.22µm: Brevundimonas diminuta
• 0.45µm: Serratia marcescens

Validation Guides are available upon request.

Quality Assurance

PTM filters are 100% integrity tested. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes. 

PTM Cartridges 

Available from 5-40 inches in length with several end connections and O-ring options. For applications using elevated temperatures, PTM/HT Cartridges can be used in processes up to 221°F. 

PTM Capsules

These filters are PTM cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. 

PTM Mini-Capsule

Mini-capsules are designed for lab scale testing, process development and small batch production with a filtration area of 500 cm².