Critical Process Filtration Blog

   Most Commonly Asked Filtration Question Series     The risks of not using vent filters on holding and mixing tanks are real and costly. Unfortunately, we usually hear from a company after they've experienced serious issues because they did not install vent filters. So, this article is written for those not yet using vent filters on their tanks. It will address the most common issues/questions we're asked on this topic with the hope of sparing you a process headache you don't need. Many processes require the use of tanks for holding ingredients to be added into the process, mixing ingredients, or holding the final product pending final filtration and filling. During the course of normal operations, these tanks will be filled and emptied many times.

Extractables and Leachables, these terms are a part of the manufacturing process of new medicines and other areas of such. These terms are very commonly misunderstood by one another and they both gave their distinct characteristics, which can be traced through the whole supply chain.  The definitions of these are not balanced. They overlap and have different utilization, and situations in the manufacturing process must be categorized to highlight the weight and necessity of both extractables and leachables.

How to evaluate a replacement filter equivalent to the one you're using now. For any number of reasons, you’re looking for a new filter supplier. If your current filtration performance is satisfactory, replacing the filters with the correct equivalent will do. But if you need to improve filter performance, a different configuration of your current filter or a different type of filter will be the solution. Either way, a quality supplier should take the time to determine exactly what equivalent means to you and help you identify the appropriate filter(s).