Whether sterilizing individual ingredients, bulk VTM, or performing a final fill into vials, our PPS filters will prevent unwanted bacteria contamination in your process, ensuring the quality and sterility of your finished VTM product. The PPS filter can be employed in your process in accordance with CDC protocols for sterile filtration of VTM.
The PPS family of pharmaceutical grade, Polyethersulfone (PES) sterilizing products are constructed with a double layer of PES membrane for greater retention while maintaining high flow and throughput. Available in cartridge, capsule and mini-capsule devices. Pore sizes recommended for VTM are 0.10 µm and 0.22µm.
PPS is a family of pharmaceutical grade, Polyethersulfone (PES) sterilizing filters. This double layered, hydrophilic filter is optimized for retention and provides added security when compared to a single layer model.
PPS filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms listed below (0.03μm, 0.10μm and 0.22μm meet the FDA definition of sterilizing grade filters). Validation Guides are available upon request.
PPS filters are 100% integrity tested. They are flushed to remove manufacturing debris and reduce extractables. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes.
Available in multiple sizes from 5-40 inches in length. Several end connections and O-rings options. For applications using elevated temperatures, PPS/HT Cartridges can be implemented up to 203°F.
These filters are PPS cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. PPS Capsules are available pre-sterilized.
Mini capsules are designed for lab testing and process development. Their overall length with inlet and outlet options range from 3.75 - 5.19 inches. PPS Mini-Capsules are available pre-sterilized.
It's simple. Our products are very competitively priced. Learn more