Viral Transport Media (VTM) Filters

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Sterile Filtration of COVID-19 Testing Media

Ensure a successful sterility check and avoid disposing of a valuable batch of media with Critical Process Filtration's PPS sterilizing filters.

Whether sterilizing individual ingredients, bulk VTM, or performing a final fill into vials, our PPS filters will prevent unwanted bacteria contamination in your process, ensuring the quality and sterility of your finished VTM product. The PPS filter can be employed in your process in accordance with CDC protocols for sterile filtration of VTM.

The PPS family of pharmaceutical grade, Polyethersulfone (PES) sterilizing products are constructed with a double layer of PES membrane for greater retention while maintaining high flow and throughput. Available in cartridge, capsule and mini-capsule devices. Pore sizes recommended for VTM are 0.10 µm and 0.22µm.

Brochure: Life Science Products

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PPS Sterilizing Filters

For the most stringent and critical applications.

  • VTM
  • Parenterals
  • Formulation & Fill
  • Diagnostics
  • Cell culture media
  • Buffers
  • Sera/plasma
  • Vaccines
  • Biologicals
  • Ophthalmics
  • WFI and Bulk Water
Features and Benefits

PES Asymmetric

PPS is a family of pharmaceutical grade, Polyethersulfone (PES) sterilizing filters.  This double layered, hydrophilic filter is optimized for retention and provides added security when compared to a single layer model. 

  • Designed to perform in the most critical applications,
  • Delivers high flow and throughput across a wide pH range
  • Low binding characteristics (much lower than cellulose acetate and nylon) for filtering liquids with preservatives and proteins that can adsorb to media
  • Pore sizes: 0.03 - 1.2 microns
Filtration Area
PPS filtration area-3
View Data Sheet for further product information:
  • Integrity test data
  • Flow rates of all pore sizes
  • Materials of construction
  • Operating parameters
  • Sanitization and sterilization
  • Regulatory & compliance

PPS Filters

PPS/HT Filters

PPS Mini-Capsules


PPS filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms listed below (0.03μm, 0.10μm and 0.22μm meet the FDA definition of sterilizing grade filters). Validation Guides are available upon request.

  • 0.03μm: Acholeplasma laidlawii 
  • 0.10μm: Brevundimonas diminuta
  • 0.22μm: Brevundimonas diminuta
  • 0.45μm: Serratia marcescens
  • 0.65μm: Saccharomyces cerevisiae
Quality Assurance

PPS filters are 100% integrity tested. They are flushed to remove manufacturing debris and reduce extractables. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes. 

PPS Cartridges 

Available in multiple sizes from 5-40 inches in length. Several end connections and O-rings options.  For applications using elevated temperatures,  PPS/HT Cartridges can be implemented up to 203°F. 

PPS cartridge        Critical Process Filtration black and white capsule with etched logo 

PPS Capsules

These filters are PPS cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. PPS Capsules are available pre-sterilized.

PPS capsule        Critical process black and white capsule with cutout to show cartridge etched logo 

PPS Mini-Capsule

Mini capsules are designed for lab testing and process development. Their overall length with inlet and outlet options range from 3.75 - 5.19 inches. PPS Mini-Capsules are available pre-sterilized. 

PPS mini     Critical Process black and white mini capsule with etched logo


Why Choose Critical Process Filters?

Quality & Performance
  • Over 20 years of engineering and manufacturing the finest filters for critical applications. 
  • Compliance with industry standards required for your operation
  • Product optimization to meet your performance goals
  • ISO 9001:2015 certified Quality Management System
  • Appropriately rated clean room environment
  • Proven success in pharmaceutical and bioprocessing applications
Price Advantage

It's simple. Our products are very competitively priced. Learn more

Services & Support
  • Presales evaluations/recommendations by highly experienced Application Engineers 
  • Post sales support and trouble shooting
  • Testing & Analysis services (our site or yours)
  • Validation Services

Made in USA 800   ISO 9001 certificate

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