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Critical Process Filtration

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Troubleshooting Integrity Testing

Troubleshooting Integrity Testing Filter integrity testing is a crucial component of maintaining a filtration system. This is particularly important for sterilizing filters used in biopharmaceutical applications. Integrity testing, conducted both

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Critical Process Filtration Nov 18, 2025

Water Intrusion Integrity Testing - Why and How

Water Intrusion Integrity Testing - Why and How Integrity testing is a vital step in ensuring a filter will perform as designed. This is especially important for sterilizing grade filters, which have been validated to demonstrate performance versus

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Critical Process Filtration May 13, 2025

Solutions for Premature Filter Fouling

Solutions for Premature Filter Fouling Filter fouling can damage a filtration system, leading to manufacturing disruptions. Properly designed systems are the best way of reducing the probability of fouling the membrane filters, but problems can and

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Critical Process Filtration Feb 11, 2025

Lowering Operating Costs and Improving Process Filter Performance

"How can I lower my operating costs AND improve process filter performance?"

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Critical Process Filtration Mar 5, 2024

Integrity Testing of Hydrophilic Membrane Filters: Diffusive Flow Test

Preface All integrity test procedures outlined below should be followed when performing integrity testing of membrane filters only. Use of these procedures on other types of filters such as polypropylene or glass fiber cartridges will not give

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Critical Process Filtration Sep 21, 2023

Case Study: Intermittent Premature Filter Fouling Solved

Premature fouling is caused by an excess of particles in the fluid that clogs a filter earlier than its expected life cycle. Typically, the problem will appear every time the fluid passes through the employed filter, and sometimes it happens

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Critical Process Filtration Mar 31, 2023

Protect Beer Quality by Removing Spoilage Organisms

The alcohol, low oxygen content, relatively low pH, hops extracts (alpha-acids) and dissolved carbon dioxide in beer inhibit the growth of pathogenic bacteria. That is why beer has been a safe drinking alternative for so many centuries. However,

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Critical Process Filtration Mar 9, 2023

Filtration Process Development and Validation in Pharmaceuticals

DEVELOPMENT, SCALE-UP, AND VALIDATION OF PHARMACEUTICAL FILTRATION PROCESSES Our Technical Service Team performs application testing for a wide variety of fluids, from water to complex chemical solutions. No matter what industry the customer is part

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Critical Process Filtration Mar 1, 2023

Pressure Decay Testing. Why, When, and How?

A simpler integrity test for less critical applications is a Pressure Decay Test. This requires the same air (or nitrogen) source and an accurate pressure gauge but does not require a mass flow meter. This type of test can be performed before and

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Critical Process Filtration May 12, 2022

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