Critical Insights Blog
Troubleshooting Integrity Testing
Troubleshooting Integrity Testing Filter integrity testing is a crucial component of maintaining a filtration system. This is particularly important for sterilizing filters used in biopharmaceutical applications. Integrity testing, conducted both
Read MoreWater Intrusion Integrity Testing - Why and How
Water Intrusion Integrity Testing - Why and How Integrity testing is a vital step in ensuring a filter will perform as designed. This is especially important for sterilizing grade filters, which have been validated to demonstrate performance versus
Read MoreSolutions for Premature Filter Fouling
Solutions for Premature Filter Fouling Filter fouling can damage a filtration system, leading to manufacturing disruptions. Properly designed systems are the best way of reducing the probability of fouling the membrane filters, but problems can and
Read MoreLowering Operating Costs and Improving Process Filter Performance
"How can I lower my operating costs AND improve process filter performance?"
Read MoreIntegrity Testing of Hydrophilic Membrane Filters: Diffusive Flow Test
Preface All integrity test procedures outlined below should be followed when performing integrity testing of membrane filters only. Use of these procedures on other types of filters such as polypropylene or glass fiber cartridges will not give
Read MoreCase Study: Intermittent Premature Filter Fouling Solved
Premature fouling is caused by an excess of particles in the fluid that clogs a filter earlier than its expected life cycle. Typically, the problem will appear every time the fluid passes through the employed filter, and sometimes it happens
Read MoreProtect Beer Quality by Removing Spoilage Organisms
The alcohol, low oxygen content, relatively low pH, hops extracts (alpha-acids) and dissolved carbon dioxide in beer inhibit the growth of pathogenic bacteria. That is why beer has been a safe drinking alternative for so many centuries. However,
Read MoreFiltration Process Development and Validation in Pharmaceuticals
DEVELOPMENT, SCALE-UP, AND VALIDATION OF PHARMACEUTICAL FILTRATION PROCESSES Our Technical Service Team performs application testing for a wide variety of fluids, from water to complex chemical solutions. No matter what industry the customer is part
Read MorePressure Decay Testing. Why, When, and How?
A simpler integrity test for less critical applications is a Pressure Decay Test. This requires the same air (or nitrogen) source and an accurate pressure gauge but does not require a mass flow meter. This type of test can be performed before and
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